Now web designers and developers can join the iPhone app party without having to learn Cocoa's Objective-C programming language. It's true: You can write iPhone apps quickly and efficiently using your existing skills with HTML, CSS, and JavaScript. This book shows you how with lots of detailed examples, step-by-step instructions, and hands-on exercises.
Nice example of an offline capable iPhone Web App
iUI is a framework consisting of a JavaScript library, CSS, and images for developing iPhone webapps